On November 11th of this season the Chargers beat the Colts 23-21 in San Diego. It’s unlikely that the Chargers will pick off Peyton Manning six times again like they did November 11th, so they will need to play mistake free football to have a chance to win on the road.
The Colts have been very good at stopping the run this season so the Chargers will need to throw the football often on first down to loosen up the Colts secondary. They will need Vincent Jackson and Chris Chambers to repeat last week’s performance against the Titans but that will likely be hard to do against corners Marlin Jackson and Kelvin Hayden. With that in mind look for a lot of passes to LaDainian Tomlinson and Antonio Gates (if he can play). That will put big pressure on outside linebackers Freddy Keiaho and Tyjuan Hagler. Still, the Chargers won’t forget to run the ball considering that they have the best running back on the planet.
The Colts will likely try to mix the run in more than usual with Joseph Addai taking on the interior of the Chargers defense. That’s because Peyton Manning had one of his worst games ever in the regular season meeting with the Chargers and Colts as he threw six pickoffs. Look for Manning to keep the passing game short to Marvin Harrison, Reggie Wayne, Anthony Gonzalez and Dallas Clark. The Colts must get good blocking from their tackles or the Colts could be in trouble with Shawne Merriman and Shaun Phillips blitzing off of the edges.
PREDICTION: COLTS 24, CHARGERS 23